We even hear now about how you can donate a lobe of your liver to someone and you can grow them a whole new liver for transplantation. Cirrhosis, the term is for the amount of scarring and damage to the liver from alcohol that is considered irreversible. And so there is kind of a point where it’s too much to recover from. And so that fatty liver, the steatosis, the scarring, the fibrosis, those things can be identified earlier and those you can recover from a lot of the time. And especially as soon as you stop drinking, the fatty liver and that kind of stuff can start to resolve.
Vitamin E deficiency, according to earlier research, makes the liver more sensitive to alcohol [97]. CYP2E1, an enzyme engaged in ethanol metabolism directly or by creating reactive oxidative metabolites, is implicated in ethanol disruption of enzymes involved in vitamin D metabolism [83,91]. The elevated levels of CYP2E1 seen in broncho-alveolar lavage fluid or liver samples of people with alcohol use disorder are likely due to this [80,92]. Alcohol use disorder affects about 7.2% of people older than 12 years old, including 6.9% of males and 7.8% of females [8]. It has been described that excessive alcohol drinking promotes the pathogenesis of many diseases, such as cancer, liver cirrhosis, cardiovascular diseases, diabetes, and neuropsychiatric disorders [9,10,11,12].
Excessive drinking can cause malabsorption, causing further vitamin deficiencies. In addition to dietary issues, alcohol affects how the body digests, stores, and uses nutrients. For example, it can decrease the secretion of digestive enzymes in the pancreas and impair nutrient absorption from the cells of the stomach or intestines. However, people who misuse alcohol may eat less food and commonly have deficiencies in zinc, magnesium, selenium, protein, and certain vitamins. Individuals with alcohol use disorder may experience deficiencies in vitamins such as vitamin B. A doctor may recommend taking supplements to help them through the detoxification process.
You should seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because best vitamins for recovering alcoholics of something you have read on this website. The NIAAA explains how alcohol affects the digestive process, which comprises the breaking down of food as it passes from the mouth, then through the stomach and intestines.
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However, alcohol consumption affects the metabolism of homocysteine (tHcy) because the enzyme cofactor for the conversion of tHcy to methionine is vitamin B12. Decreased levels of vitamin B12 levels were shown to be adversely connected with tHcy and significantly linked with indicators of alcohol-related liver impairment in recent research [52]. Another research found that individuals with severe chronic liver disease had high vitamin B12 plasma levels but decreased vitamin B9 plasma levels [53].
Hcy is metabolized by cystathionine beta-synthase (CBS) and cystathionase to produce cysteine and glutathione (GSH) in transsulfuration processes. It is also important to note that SAM inhibits MTHFR while promoting CBS expression. As a result, a SAM shortage boosts 5-Methyl THF production while lowering 5,10-Methyl THF and GSH production. Here’s everything you need to know about using herbal supplements for alcohol withdrawal.
However, the most powerful (and empowering) diets help you focus instead on what you can and should eat. In fact, research shows that adding certain foods to your diet is just as important as cutting back on others. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Reduced glutathione (GSH) and vitamins are probably the most important nonenzymatic antioxidants and participate in a wide range of cellular functions. Furthermore, internal redox buffers, such as Hcy, cysteine (Cys), and cysteinyl glycine (CysGly), play an important role in the extracellular redox system [108,109]. Chronic alcohol intake produces altered Hcy metabolism, which leads to fat storage, inflammation, and hepatocyte damage [110,111]. Hyperhomocysteinemia induced by ethanol and linked to oxidative endoplasmic reticulum stress triggers apoptosis and increases lipid production [112].
However, heavy drinkers experiencing severe side effects might consider the following additional supplements. While taking vitamins can’t “cure” the consequences of increased alcohol intake, they play a critical role in the recovery of chronic alcoholics. Previous research has linked alterations in methionine metabolism to ethanol-induced alcoholic liver damage [113,114,115]. In animals and humans, chronic ethanol abuse reduces plasma levels of vitamins such as vitamin B9 and hepatic levels of SAMe [116] and raises plasma Hcy and hepatic S-adenosylhomocysteine (SAH) concentrations [110,114,115]. This substance has been shown to cause deficiencies in essential nutrients, including vitamins and minerals that are needed to support detoxification and other biochemical processes. If you have been drinking to excess, be sure to educate yourself about how exactly alcohol causes nutrient deficiencies.